A securely stored modern certificate is going to be magnitudes more secure than password plus MFA.

The certificate path uses cryptography to prevent disclosure of your secret, and can't be compromised when the site inevitably gets hacked.

I wouldn't classify passkeys as MFA tho, they are a passwordless method that's more secure than most MFA methods. Afaik it's based on signed certificates or something like that and that's virtually unhackable unless someone gets physical access to your device (and that's game over anyway).

If you're using software that properly uses your device's SE / TPM chip then it's much more secure against malware, etc. And the main selling point is the much stronger phishing resistance (can't trick you into logging in via a fake site, etc)