Console? good, GUI? good, game dev? use Godot engine with its similar language Gdscript, but what else? Ive been seeing AI, Data Science stuff, but whats the point if ita slow?
In my experience, GUI was horrible because of the GIL. Python is nice because you can write and read it quickly, and packages like numpy allow you to use very natural syntax. Most of the numerical packages wrap C/C++/Fortran binaries which are very optimized. You just have to keep in mind not to do that kind of stuff directly in Python, write tight loops, etc.