Just go for it. You can always go back to stock if you dont like it.
My advice: dont make it too complicate. GOS has a lot of different securities and you can choose whatever you want to do with your phone. Some examples::
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you can run the whole thing on 1 profile
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1 main profile and 1 secondary for Google
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1 main profile for admin and several secondary profiles each with their own private space... .
and so on and on. I like to think of GOS similar to Archlinux. You can choose your way, but if things go south , a extremely complicate setup will make it very difficult to diagnose and maintain.