Indeed I don’t have high expectations that something exists. My 1st thought was perhaps this is something that should have some R&D on it. Particularly for ticks (as early detection is critical for Lym disease). But then I figured I should first find out if something already exists.. hence the post.
Regarding inflammation, I was thinking about how part of the bedbug’s evil cocktail is not just an anesthetic, but also a chemical to vasodialate to get blood vessels opened up more. I wasn’t sure if Ibuprofin would have interplay with that.. but you’re probably right.. the anti-inflamatory would not likely counteract an anti-anesthetic.
Reminds me of a fun trick I heard about w/mosquitos. If a mosquito lands on your arm, you can pinch off your own blood supply to the arm which causes the mosquito to react by going deeper and sucking harder. Then you release your blood and let it rush, at which point the mosquito’s pipeline gets flooded and the mosquito explodes with a “pop”. Never tried it myself.