There are better antibiotics, which work with less frequent doses, but they’re only given out when medically necessary. I assume having bill gates’ wealth (and control of a whole bunch of anti malaria initiatives) means you have access to the kind of antibiotic you choose, you can even justify it by saying that you’re bill gates and you have a sixty hour workweek with the foundation, even in retirement, and you simply cannot take more than two days off, but antibiotics make you feel too weird to work, if you want.