Hyperbole is a common form of expression in abstractive thought. It is a problem I've dealt with a lot in my life. Complete loss can still have many meanings in terms of the layer of inhabitation the person is referring to. They could be referring to their own internal perception of social anxiety, decision making, or an overall perception of their potential to actuate meaningful change in their life. Given the context of 'talking to random NPCs', the most likely meaning is a loss of social anxiety.